Details
- Manufacturer: Research Diagnostics
- Mfr. Cat. # RDIPRO610108
Lab Supply » Immunology/Oncology » Cell Biology
Uroplakin III clone AU1
Medix Item Code: RDU-0108
$476.80 per Ea.
List Price: $576.40
You Save: $99.60 (17%)
Size: 50ug (lyophilized)
Special shipping requirements
- Refrigerated - This item is refrigerated and must ship by air with ice.
Description
Mab AU1 reacts specifically with uroplakin III present in the superficial cell layer of the urothelium. Antibody AU1 strongly stains the urothelial surface membrane in paraffin sections of human renal pelvis, ureter, bladder, and uretha. About 60% of human transitional cell carcinomas (including metastases) maintain focal (sometimes very limited) expression of uroplakin III. Until know, no uroplakin staining was found in any non-urothelial carcinoma (Moll et al 1995). Uroplakin III may thus serve as a specific urothelial differentiaition marker in cases of metastatic carcinomas with unclear primary tumor
